| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20190515120622.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190515b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
8541 |
| Author |
Girish, K. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Synthesis and Antibacterial Activity of Cobalt(II) Complex of Curcumin |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol. 81(1), Jan-Feb |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Journal of Pharmaceutical Science |
| Year |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
150-155p. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
To improve the bioavailability of curcumin numerous approaches were attempted, which included complexation with metal ions. In the present study, a metal ion complex of cobalt(II) with curcumin was synthesized and screened for in vitro antibacterial activity in comparison with curcumin on seven bacterial strains, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Shigella flexneri, Proteus vulgaris and Staphylococcus aureus. The cobalt-curcumin complex was effective against all strains tested and the activity was greater than that exhibited by curcumin. Comparison of the inhibitory activity with the macrolide antibiotic azithromycin revealed that cobalt-curcumin complex was as active as the antibiotic. The cobalt-curcumin complex could be a suitable candidate for further in vivo investigations. This is the first report of antibacterial activity of cobalt-curcumin complex against all the bacterial strains tested except Escherichia coli. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
8542 |
| Co-Author |
Channu, B. C. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
8543 |
| Co-Author |
Baba, A. R. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Indian journal of pharmaceutical sciences |
| Place, publisher, and date of publication |
New Delhi Indian Pharmaceutical Association |
| International Standard Serial Number |
0250-474X |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| URL |
http://www.ijpsonline.com/articles/synthesis-and-antibacterial-activity-of-cobaltii-complex-of-curcumin.pdf |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
