| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20190919093915.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
190919b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
9538 |
| Author |
Voycheva, Ch. Tch. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Formulation of Tablets Containing Glimepiride-loaded Mesoporous Silica Particles |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol. 81(3), May-June |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Journal of Pharmaceutical Science |
| Year |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
483-488p. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The aim of the present study was to develop a tablet formulation with improved dissolution of glimepiride. Glimepiride was loaded into two types of mesoporous silica particles via solvent-incubation method. Physicochemical characterization of the particles was carried out by transmission electron microscopy, infrared spectroscopy, dynamic light scattering and thermogravimetric analysis. Flowability and compressibility characteristics of the powder mixtures, containing pure glimepiride as well as both types of drug-loaded silica particles and excipients were evaluated by bulk and tapped density and angle of repose. Tablets were prepared by direct compression method and consequently tested for hardness, friability, disintegration and in vitro release properties. In vitro release studies demonstrated that the glimepiride dissolution rate was notably improved from tablets prepared with both types mesoporous silica particles as compared with the bulk drug. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
9539 |
| Co-Author |
Tzankov, B. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
New Delhi Indian Pharmaceutical Association |
| International Standard Serial Number |
0250-474X |
| Title |
Indian journal of pharmaceutical sciences |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| URL |
http://www.ijpsonline.com/articles/formulation-of-tablets-containing-glimepirideloaded-mesoporous-silica-particles.pdf |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
