Current updates on diagnostic biomakers of hepatocellular Carcinoma (Record no. 9533)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20190924115951.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190924b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 7214 |
| Author | Hasan, N. |
| 245 ## - TITLE STATEMENT | |
| Title | Current updates on diagnostic biomakers of hepatocellular Carcinoma |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol. 56 (06) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Drug Manufacture's Association - IDMA |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 7-23 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Hepatocellular carcinoma (HCC) is a liver malignancy, which is a cause of several deaths related to cancer worldwide. In early stages, curative treatment such as surgical resection, liver transplant and local ablation can improve the patient’s survival. However, the disease is often diagnosed in an advanced stage; moreover, some available therapies are restricted to palliative care and local treatment. Early diagnosis of HCC and adequate therapy are crucial to increasing survival as well as to improve the patient’s quality of life. Therefore, many researchers have been investigating biomarkers such as alpha-fetoprotein (AFP), glypican-3 (GPC3), des-γ-carboxyprothrombin, gamma-glutamyl transferase (GGT), serum α-L-fucosidase (AFU), carbonyl reductase 2, golgi phosphoprotein 2, transforming growth factor-β1 (TGF-β1), vascular endothelial growth factor (VEGF), tumor- specific growth factor (TSGF), epidermal growth factor receptor family (EGFR), hepatocyte growth factor/scatter factor, fibroblast growth factor (FGF), circulating nucleic acids (mRNAs), gamma-glutamyl transferase mRNA (GGT mRNA), insulin-like growth factor II (IGF-II) mRNA, albumin mRNA, circulating micro RNAs, heat shock protein (HSP), Golgi protein 73 (GP73), squamous cell carcinoma antigen (SCCA), tumor-associated glycoprotein 72 (TAG-72), zinc-α2-glycoprotein (ZAG), cytokeratin 19, osteopontin, midkine (MDK), gankyrin, annexin A2, soluble urokinase plasminogen activator receptor (suPAR), AXL, thioredoxins (TRXs), cluster of differentiation 147 (CD147) and microRNAs, which can regulate important pathways in carcinogensis, tumor angiogenesis and progression. So, they can be considered as possible markers of progression in HCC and therapeutic targets for this type of cancer. In this review, we discuss the recent advances related to diagnostic biomarkers, clinical aspects and outcome in hepatocellular carcinoma. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 9617 |
| Co-Author | Mukim, M. |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Mumbai Indian Drug Manufactures Association |
| Title | Indian drugs |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.indiandrugsonline.org/issuesarticle-details?id=OTM2 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2019-09-24 | 2019716 | 2019-09-24 | 2019-09-24 | Articles Abstract Database |