000 -LEADER |
fixed length control field |
a |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20191018104334.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
191018b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
AIKTC-KRRC |
Transcribing agency |
AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME |
9 (RLIN) |
9925 |
Author |
Padhi, Swarupanjali |
245 ## - TITLE STATEMENT |
Title |
Development and Application of Lipid Nanotechnology on Infectious Diseasesof CNS- Current Scenario |
250 ## - EDITION STATEMENT |
Volume, Issue number |
Vol.53(3), Jul-Sep |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Karnataka |
Name of publisher, distributor, etc. |
Indian journal of pharmaceutical education and research |
Year |
2019 |
300 ## - PHYSICAL DESCRIPTION |
Pagination |
355-365p. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Background: This is an era of inventive technology illuminating fundamental mechanisms of diseases and fabricating drug molecules according to prerequisite condition, but it is still a challenge to target infectious diseases specially in CNS due to various restrictions of drug delivery to the brain and drawbacks of various conventional antimicrobial agents. These are prone to development of multiple drug resistances as sufficient amount of drug cannot reach to the site of infection. Materials and Methods: This review summarizes the problems associated with the amount of drug delivered to CNS and the emergence of new tools like lipid nanoparticles to deal with the current challenges in treating infectious diseases of CNS. Results: This article discusses the anatomical and physiological barriers of CNS and development of various drug delivery system, specially the development of lipid nanoparticles including solid lipid nanoparticles, nanostructured lipid carriers, lipid drug conjugated nanoparticles to address the challenges. Conclusion: This article is an extensive review on current status of drug therapy of infectious diseases of CNS. Lipid nanoparticles like SLN and NLCs have proven to be effective tools for improved drug delivery to CNS and PNS. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
9 (RLIN) |
4639 |
Topical term or geographic name entry element |
PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
9926 |
Co-Author |
Mazumder, Rupa |
773 0# - HOST ITEM ENTRY |
Place, publisher, and date of publication |
Bengluru Association of Pharmaceutical Teachers of India (APTI) |
International Standard Serial Number |
0019-5464 |
Title |
Indian journal of pharmaceutical education and research |
856 ## - ELECTRONIC LOCATION AND ACCESS |
URL |
https://www.ijper.org/sites/default/files/IndJPhaEdRes_53_3_355_365.pdf |
Link text |
Click here |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Koha item type |
Articles Abstract Database |