Pharmacological evaluation of in vitro anti-oxidant and in vivo anti-depressant activity of ethanolic bark extracts of annona muricata on mice (Record no. 9895)

000 -LEADER
fixed length control field a
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20191030155906.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 191030b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 6961
Author Ravishankar, K.
245 ## - TITLE STATEMENT
Title Pharmacological evaluation of in vitro anti-oxidant and in vivo anti-depressant activity of ethanolic bark extracts of annona muricata on mice
250 ## - EDITION STATEMENT
Volume, Issue number Vol.56(9), Sep
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Drug Manufacture's Association - IDMA
Year 2019
300 ## - PHYSICAL DESCRIPTION
Pagination 61-67p.
520 ## - SUMMARY, ETC.
Summary, etc. The aim of the present work was to evaluate the anti-oxidant and anti-depressant potentials of the Ethanolic bark extract of Annona muricata. Ethanolic bark extracts of Annona muricata was subjected to preliminary and quantitative phytochemical screening. In vitro Anti-oxidant activity of Annona muricata was performed using phosphomolybdenum assay with Ascorbic acid as the standard. As the extract exhibited potent anti-oxidant activity, it was investigated further for its anti-depressant activity using Forced swim test(FST), Tail suspension test(TST), Digital photoactometer test (DPT) and Open field test(OFT). Imipramine & Fluoxetine [10mg/kg] were used as reference drugs for the anti-depressant experiments. Ethanolic Bark extract of Annona muricata exhibited significant anti-oxidant activity with significant increase of absorbance in a concentration dependent manner while in anti-depressant activity there was considerable decrease in the immobility time . Altogether, these results suggest that the Ethanolic bark extract of Annona muricata could be used as a potential anti-oxidant and anti-depressant agent.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 10182
Co-Author Sowmya, P.V.S.C.P.
773 0# - HOST ITEM ENTRY
Title Indian drugs
Place, publisher, and date of publication Mumbai Indian Drug Manufactures Association
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.indiandrugsonline.org/issuesarticle-details?id=OTgw
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2019-10-30 2020032 2019-10-30 2019-10-30 Articles Abstract Database
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