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Review on Perflutren, A Diagnostic Drug that is intended to be used for contrast enhancement during the indicated Echocardiographic procedures

By: Jain, Mayur S.
Contributor(s): Barhate, Shashikant D.
Publisher: Raipur Asian Pharma Press 2019Edition: Vol.9(3), Jul-Sep.Description: 190-192p.Subject(s): PHARMACEUTICSOnline resources: Click here In: Asian journal of pharmaceutical researchSummary: Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.1,2
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Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.1,2

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