Concise formal synthesis of (-)-(6R,11R,14R)-colletallol via D-proline catalysed α-aminooxylation-Wittig olefination strategy
By: Dey, Soumen
.
Contributor(s): Gadakh, Sunita.
Publisher: New Delhi CSIR 2019Edition: Vol.58B(9), Sep.Description: 1029-1036p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: An efficient enantioselective formal synthesis of marine macrolide (−)-(6R,11R,14R)-colletallol has been achieved starting from commercially available raw materials. The key reactions include the D-proline catalyzed α-aminooxylation of aldehyde followed by Horner-Wardsworth-Emmons olefination in a sequential fashion to give the macrolide key intermediate 5 in high enantiomeric purity (97% ee) and high overall yield (32%).
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
|
School of Pharmacy Archieval Section | Not for loan | 2020684 |
Total holds: 0
An efficient enantioselective formal synthesis of marine macrolide (−)-(6R,11R,14R)-colletallol has been achieved starting from commercially available raw materials. The key reactions include the D-proline catalyzed α-aminooxylation of aldehyde followed by Horner-Wardsworth-Emmons olefination in a sequential fashion to give the macrolide key intermediate 5 in high enantiomeric purity (97% ee) and high overall yield (32%).
Click on an image to view it in the image viewer
There are no comments for this item.