Synthesis of dihydro-1,4-thiazine from α-keto spiro-thiazolidine
By: Utsukihara, Takamitsu
.
Contributor(s): Matsushita, Masatoshi.
Publisher: New Delhi CSIR 2019Edition: Vol.58B(9), Sep.Description: 1037-1041p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: The reaction of α-bromocycloalkanone with 2-aminoethanthiol leads to the regioselective formation of spirothiazolidin-2-one with the oxo-group migrating to the original position occupied by the halogen atom. The reaction of 1-thia-4-azaspiro[4.5]alkan-6-one with bromine, iodine, copper (II) salts, acid or base gives dihydro-1,4-thiazine derivatives in moderate yields. Moreover, the treatment of the spiro-thiazolidine derivatives on silica gel under microwave gives the 1,4-thiazine compound.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
|
School of Pharmacy Archieval Section | Not for loan | 2020685 |
Total holds: 0
The reaction of α-bromocycloalkanone with 2-aminoethanthiol leads to the regioselective formation of spirothiazolidin-2-one with the oxo-group migrating to the original position occupied by the halogen atom. The reaction of 1-thia-4-azaspiro[4.5]alkan-6-one with bromine, iodine, copper (II) salts, acid or base gives dihydro-1,4-thiazine derivatives in moderate yields. Moreover, the treatment of the spiro-thiazolidine derivatives on silica gel under microwave gives the 1,4-thiazine compound.
Click on an image to view it in the image viewer
There are no comments for this item.