Synthesis, characterization and crystallographic analysis of N-2-(tert-butylcarbomyl) (4-chlorophenyl methyl)-6-fluoro-N- (3, 4, 5-triethoxyphenyl) chroman-2-carboxamide
By: Kapadiya, Khushal
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Contributor(s): Dhaduk, Bhavin.
Publisher: New Delhi CSIR 2019Edition: Vol.58B(8), Aug.Description: 944-948p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
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Indian journal of chemistry (Section B)Summary: The title compound (UGCl 001) has been prepared by the multicomponent reaction of chromanes (U-4CC) without using catalyst. The compound has been characterized by 1H and 13C NMR, IR and MS techniques. X-ray crystallographictechnique has been applied and the results show that the crystal belongs to the triclinic system having space group P-1(#2) with unit cell parameters, a = 10.704(2) Å, b = 12.843(2) Å, c = 13.179(2) Å, α = 116.968(4)°, β = 103.203(4)°, γ = 95.788(5)°, V = 1527.8(4) Å3 and Z = 2. In the title compound, dihedral angles between the planes of the chromane ring (A), substituted aniline ring (B), substituted benzaldehyde (C) and tert-butyl isocynides (D) are 121.2 (3), 123.0(2) and 113.0(3) respectively. Intermolecular N---O, C---Cl and C---F interaction has been found in the crystal structure and results in a three dimensional network structure.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2020802 |
The title compound (UGCl 001) has been prepared by the multicomponent reaction of chromanes (U-4CC) without using catalyst. The compound has been characterized by 1H and 13C NMR, IR and MS techniques. X-ray crystallographictechnique has been applied and the results show that the crystal belongs to the triclinic system having space group P-1(#2) with unit cell parameters, a = 10.704(2) Å, b = 12.843(2) Å, c = 13.179(2) Å, α = 116.968(4)°, β = 103.203(4)°, γ = 95.788(5)°, V = 1527.8(4) Å3 and Z = 2. In the title compound, dihedral angles between the planes of the chromane ring (A), substituted aniline ring (B), substituted benzaldehyde (C) and tert-butyl isocynides (D) are 121.2 (3), 123.0(2) and 113.0(3) respectively. Intermolecular N---O, C---Cl and C---F interaction has been found in the crystal structure and results in a three dimensional network structure.
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