ANTIVIRAL DRUGS FOR INFLUENZA VIRUSES
By: Haque, SK Manirul.
Contributor(s): Elzagheid, Mohamed Ibrahim.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2019Edition: Vol.11(5).Description: 1-8p.Subject(s): PHARMACEUTICSOnline resources: Click here In: International journal of pharmacy and pharmaceutical scienceSummary: Antiviral drugs have significant action against inf luenza viruses A and B. Virus spread deadly disease in which many people die, and the country economy greatly suffer. Presently, most of the peop le need to get vaccination, which is depending on t he dose limit in humans. It reacts directly or sometimes indirectly in the form of metabolites. How ever, it is mandatory to know how much drug is abso rbed or metabolites concentration after administered. Therefore, pharmacokinetics data is v ery crucial for all drugs. Our review discusses the mechanism of drugs action and their activity and also describes how antiviral drugs and their me tabolites are determined using highly sensitive ins truments such as high-performance liquid chromatography (HPLC), ultra-pressure liquid chromat ography (UPLC), and mass spectrometry (MS). Therefo re, the present review gives brief information about antiviral drugs, their activity, biotransformation and analytical methods for quanti fication and this information will be helpful for any future studies done by experts in this field an d will be beneficial for research scientists and in fluenza experts of all over the globe.Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database | School of Pharmacy Archieval Section | Not for loan | 2020920 |
Antiviral drugs have significant action against inf
luenza viruses A and B. Virus spread deadly disease
in which many people die, and the country
economy greatly suffer. Presently, most of the peop
le need to get vaccination, which is depending on t
he dose limit in humans. It reacts directly or
sometimes indirectly in the form of metabolites. How
ever, it is mandatory to know how much drug is abso
rbed or metabolites concentration after
administered. Therefore, pharmacokinetics data is v
ery crucial for all drugs. Our review discusses the
mechanism of drugs action and their activity
and also describes how antiviral drugs and their me
tabolites are determined using highly sensitive ins
truments such as high-performance liquid
chromatography (HPLC), ultra-pressure liquid chromat
ography (UPLC), and mass spectrometry (MS). Therefo
re, the present review gives brief
information about antiviral drugs, their activity,
biotransformation and analytical methods for quanti
fication and this information will be helpful for
any future studies done by experts in this field an
d will be beneficial for research scientists and in
fluenza experts of all over the globe.
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