Study of Prescribing Patterns for Non-Steroidal Anti- Inflammatory Drugs in a Tertiary Care Teaching Hospital
By: Kandasamy, Geetha
.
Contributor(s): ALMAGHASLAH, DALIA.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2021Edition: Vol.83(2), March-April.Description: 287-292p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical sciencesSummary: Analgesics including nonsteroidal anti-inflammatory drugs are a commonly prescribed group of drugs
in clinical practice for the management of pain and inflammation. This study was carried out to evaluate
the prescribing pattern for nonsteroidal anti-inflammatory drugs in the tertiary care teaching hospital.
A prospective cross sectional study was conducted in the orthopaedic department of a tertiary care
teaching hospital from February to December 2017. The institutional ethical committee approved the
study. Patients of both genders were included in the study. Patients treated with at least one nonsteroidal
anti-inflammatory drug in the outpatient department of orthopaedics were included. The prescription
was compared with World Health Organization drug prescribing indicators to compare selective and non-
selective nonsteroidal anti-inflammatory drugs associated with the treatment also concurrent prescription
of gastro protective agents. The data collected was analysed by descriptive statistics. Chi-Square test was
used to compare the difference between the two groups. A p value of <0.05 was considered significant. Out
of 500 prescriptions included in the study, the total number of drugs prescribed was 1098, of which were
nonsteroidal anti-inflammatory drugs. Based on the World Health Organization’s drug use indicators,
the average number of drugs per encounter was 2.19 % and the average number of nonsteroidal anti-
inflammatory drugs per encounter was 1.38 %. Out of all the nonsteroidal anti-inflammatory drugs
prescribed, 428 (62.20 %) were from National List of Essential Medicine India 2015 and 678 (98.5 %)
nonsteroidal anti-inflammatory drugs were prescribed by generic name. Among the study population,
only 40 % of patients were prescribed Proton Pump Inhibitors along with nonsteroidal anti-inflammatory
drugs. Proton Pump Inhibitors are effective in ulcer prophylaxis in their standard dose. The present
study concluded that among cyclooxygenase-1 inhibitors, Diclofenac was the most commonly prescribed
nonsteroidal anti-inflammatory drugs from the national list of essential medicine. The most frequently
prescribed cyclooxygenase-2 inhibitor in this study was Etoricoxib. The percentage of analgesic prescribed
by generic name was excellent. However, the average number of drugs per prescription deviated from the
World Health Organization’s rational drug use indicator. The use of gastro protective agents needs to be
rationalised with nonsteroidal anti-inflammatory drugsy
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2021-2022599 |
Analgesics including nonsteroidal anti-inflammatory drugs are a commonly prescribed group of drugs
in clinical practice for the management of pain and inflammation. This study was carried out to evaluate
the prescribing pattern for nonsteroidal anti-inflammatory drugs in the tertiary care teaching hospital.
A prospective cross sectional study was conducted in the orthopaedic department of a tertiary care
teaching hospital from February to December 2017. The institutional ethical committee approved the
study. Patients of both genders were included in the study. Patients treated with at least one nonsteroidal
anti-inflammatory drug in the outpatient department of orthopaedics were included. The prescription
was compared with World Health Organization drug prescribing indicators to compare selective and non-
selective nonsteroidal anti-inflammatory drugs associated with the treatment also concurrent prescription
of gastro protective agents. The data collected was analysed by descriptive statistics. Chi-Square test was
used to compare the difference between the two groups. A p value of <0.05 was considered significant. Out
of 500 prescriptions included in the study, the total number of drugs prescribed was 1098, of which were
nonsteroidal anti-inflammatory drugs. Based on the World Health Organization’s drug use indicators,
the average number of drugs per encounter was 2.19 % and the average number of nonsteroidal anti-
inflammatory drugs per encounter was 1.38 %. Out of all the nonsteroidal anti-inflammatory drugs
prescribed, 428 (62.20 %) were from National List of Essential Medicine India 2015 and 678 (98.5 %)
nonsteroidal anti-inflammatory drugs were prescribed by generic name. Among the study population,
only 40 % of patients were prescribed Proton Pump Inhibitors along with nonsteroidal anti-inflammatory
drugs. Proton Pump Inhibitors are effective in ulcer prophylaxis in their standard dose. The present
study concluded that among cyclooxygenase-1 inhibitors, Diclofenac was the most commonly prescribed
nonsteroidal anti-inflammatory drugs from the national list of essential medicine. The most frequently
prescribed cyclooxygenase-2 inhibitor in this study was Etoricoxib. The percentage of analgesic prescribed
by generic name was excellent. However, the average number of drugs per prescription deviated from the
World Health Organization’s rational drug use indicator. The use of gastro protective agents needs to be
rationalised with nonsteroidal anti-inflammatory drugsy
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