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Biosynthesis of iron nanoparticles from pleurotus florida and its antimicrobial activity against selected human pathogens

By: Manikandan, G.
Contributor(s): Ramasubbu, R.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2021Edition: Vol.83(1), Jan-Feb.Description: 45-51p.Subject(s): PHARMACEUTICSOnline resources: Click here In: Indian journal of pharmaceutical sciencesSummary: In the present investigation, iron nanoparticles were synthesized by using mushroom extract. The production of iron nanoparticles from Pleurotus florida was initially con firmed by color changes from brown to dark brown within 30 min at 60° and further characterized by Ultraviolet-Visible spectroscopy and scanning electron microscope with Edax. The biosynthesized iron nanoparticles were subjected to antimicrobial activities and showed higher zone of inhibition against Candida glabrata followed by Micrococcus mucilaginosus , Pseudomonas aeruginosa , Candida albicans , Klebsiella terrigena , Klebsiella pneumoniae, Escherichia coli, Candida sp., Bacillus cereus and Staphylococcus aureus. This extract was confirmed as effective against microorganisms which was well comparable with standard antibiotics. The present study has recommended that iron nanoparticles from mushrooms have great potential to act as safe alternative to antibiotics to fight the challenges of drug discovery
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In the present investigation, iron nanoparticles were synthesized by using mushroom extract. The
production of iron nanoparticles from Pleurotus florida was initially con firmed by color changes from
brown to dark brown within 30 min at 60° and further characterized by Ultraviolet-Visible spectroscopy
and scanning electron microscope with Edax. The biosynthesized iron nanoparticles were subjected to
antimicrobial activities and showed higher zone of inhibition against Candida glabrata followed by
Micrococcus mucilaginosus , Pseudomonas aeruginosa , Candida albicans , Klebsiella terrigena , Klebsiella
pneumoniae, Escherichia coli, Candida sp., Bacillus cereus and Staphylococcus aureus. This extract was
confirmed as effective against microorganisms which was well comparable with standard antibiotics. The
present study has recommended that iron nanoparticles from mushrooms have great potential to act as
safe alternative to antibiotics to fight the challenges of drug discovery

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