Unique synthesis of isochromenoindolone via reductive-oxidative cyclisation approach
By: Kadam, Hari K
.
Contributor(s): Tilve, Santosh G.
Publisher: New Delhi CSIR 2021Edition: Vol.58(B), Jan.Description: 104-108p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: Fused heterocyclic compounds are extensively studied
in medicinal chemistry due to their promising
biological properties such as anticancer, antiviral,
antimicrobial activities, etc.1-4 Such compounds also
find a resemblance to the constituent structures of
important natural products5-9 (Figure 1).
Indole and isochromane based heterocyclic
structures are found in several medicinally important
compounds hence a fused convergent structural motif
promises interesting biological properties10-13.
Isochromenoindolone is one such compound with
probable lead to a new class of bioactive
compounds14−17. Anticipating a vast potential for
medicinal studies for this compound, we directed our
efforts towards developing a simple, efficient and
versatile method for synthesis of isochromeno[4,3-
b]indol-5(11H)-one.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
|
School of Pharmacy Archieval Section | Not for loan | 2022-0291 |
Fused heterocyclic compounds are extensively studied
in medicinal chemistry due to their promising
biological properties such as anticancer, antiviral,
antimicrobial activities, etc.1-4 Such compounds also
find a resemblance to the constituent structures of
important natural products5-9 (Figure 1).
Indole and isochromane based heterocyclic
structures are found in several medicinally important
compounds hence a fused convergent structural motif
promises interesting biological properties10-13.
Isochromenoindolone is one such compound with
probable lead to a new class of bioactive
compounds14−17. Anticipating a vast potential for
medicinal studies for this compound, we directed our
efforts towards developing a simple, efficient and
versatile method for synthesis of isochromeno[4,3-
b]indol-5(11H)-one.
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