New antimicrobial pentacyclic triterpenoid from the rhizomes of Nardostachys jatamansi DC.
By: Singh, Ajay Pal
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Contributor(s): Sharma, Surendra Kumar.
Publisher: New Delhi CSIR 2019Edition: Vol.58(B), April.Description: 516-521p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: Phytochemical investigation of Nardostachys jatamansi rhizomes has resulted in isolation of a new pentacyclic triterpenoid lup-20 (29)-en-3β-olyl-3β--galactofuranosyl-6'-octadec-9''-enoate 4 along with three phytoconstituents characterized as 1-octadec-9',10'-dienoyl-2,3-n-dioctadecanoyl glycerol 1, n-octanyl-n-octadecanoate 2, n-nonyloctadecanoate 3. The structures of all the isolated compounds have been elucidated on the basis of spectral data analysis such as IR, 1H and 13C NMR, mass spectroscopy and chemical reactions. Compounds 1, 2, 3 have been reported first time from Nardostachys genus. The isolated phytoconstituents have been tested for antimicrobial activity against bacterial and fungal strains. Only compound 4 shows antimicrobial activity.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-0326 |
Phytochemical investigation of Nardostachys jatamansi rhizomes has resulted in isolation of a new pentacyclic triterpenoid lup-20 (29)-en-3β-olyl-3β--galactofuranosyl-6'-octadec-9''-enoate 4 along with three phytoconstituents characterized as 1-octadec-9',10'-dienoyl-2,3-n-dioctadecanoyl glycerol 1, n-octanyl-n-octadecanoate 2, n-nonyloctadecanoate 3. The structures of all the isolated compounds have been elucidated on the basis of spectral data analysis such as IR, 1H and 13C NMR, mass spectroscopy and chemical reactions. Compounds 1, 2, 3 have been reported first time from Nardostachys genus. The isolated phytoconstituents have been tested for antimicrobial activity against bacterial and fungal strains. Only compound 4 shows antimicrobial activity.
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