Synthesis, Hammett spectral correlation and evaluation of antimicrobial activities of some substituted styryl 4'-piperidinophenyl ketones
By: Ranganathan, K.
Contributor(s): Kamalakkannan, D.
Publisher: New Delhi CSIR 2019Edition: Vol.58(B), Oct.Description: 1131-1143p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here In: Indian journal of chemistry (Section B)Summary: A series containing twelve substituted 4'-piperidinophenyl chalcones have been synthesized from crossed-aldol condensation between 4-piperidionphenyl methyl ketone and substituted benzaldehydes using solid Cu2+/Zeolite catalyzed microwave assisted method. The structures of chalcones have been characterized by their physical constants, analytical and spectral data. The observed spectral frequencies have been correlated with Hammett substituents, F and R parameters using both single and multi-regression analyses. All the substituted 4'-piperidinophenyl chalcones have been tested for antimicrobial activities using disc diffusion method.Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database | School of Pharmacy Archieval Section | Not for loan | 2022-0341 |
A series containing twelve substituted 4'-piperidinophenyl chalcones have been synthesized from crossed-aldol condensation between 4-piperidionphenyl methyl ketone and substituted benzaldehydes using solid Cu2+/Zeolite catalyzed microwave assisted method. The structures of chalcones have been characterized by their physical constants, analytical and spectral data. The observed spectral frequencies have been correlated with Hammett substituents, F and R parameters using both single and multi-regression analyses. All the substituted 4'-piperidinophenyl chalcones have been tested for antimicrobial activities using disc diffusion method.
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