One-pot two-step facile synthesis of new 6,7-dihydro-1H—pyrazolo [3,4-b] pyridine-5- carbonitrile hybrids as antimicrobial agents
By: Tiwari, Shailendra
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Contributor(s): Akeel Ahmad.
Publisher: New Delhi CSIR 2019Edition: Vol.58(B), Dec.Description: 1407-1412p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: A new series of novel 1-benzoyl-4-(4-aroyl/aroyloxy methyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo [3,4-b] pyridine-5-carbonitrile have been synthesized from a common intermediate, in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria and fungi. The minimum inhibitory concentration (MBC) and minimum fungicidal concentration (MFC) have been determined for the test compounds as well as for reference standards. Compounds 3c, 3f, 3h, 3i, 3n, 3o, 3p have shown good antibacterial activity where as compounds 3b, 3e, 3g, 3i, 3p have displayed better antifungal activity.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-0350 |
A new series of novel 1-benzoyl-4-(4-aroyl/aroyloxy methyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo [3,4-b] pyridine-5-carbonitrile have been synthesized from a common intermediate, in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria and fungi. The minimum inhibitory concentration (MBC) and minimum fungicidal concentration (MFC) have been determined for the test compounds as well as for reference standards. Compounds 3c, 3f, 3h, 3i, 3n, 3o, 3p have shown good antibacterial activity where as compounds 3b, 3e, 3g, 3i, 3p have displayed better antifungal activity.
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