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Biofibgel: a green nanotechnology based wound dressing

By: Shandilya, Garima.
Contributor(s): Tarwadi, Kirtan.
Publisher: Karnataka Association of Pharmaceutical Teachers of India (APTI) 2021Edition: Vol.55(4), Oct-Dec.Description: 979-988p.Subject(s): PHARMACEUTICSOnline resources: Click here In: Indian journal of pharmaceutical education and researchSummary: Aim: Wound is a fragile and complex injury which can be as simple as a minor cut to the deep lesions and traumatic gash. Depending on the patient’s internal and external conditions, wounds can progress backward or forward. Acute hemorrhage and wound infections are the main cause of loss of life in critical conditions of war field or in traumatic accidents. Innovation: BioFibGel bandage/dressing is a green nanotechnology based wound care product which is intended to be used in trauma, combat injuries (bleeding gunshot wounds) and mangling as first-line emergency tool. The dressing can absorb and retain significant amount of water without dissolving or losing their structure, stabilize blood flow and avert bleeding. Materials and Results: BioFibGel is silver nanoparticles based hydrogel sheets/ fibers made up of gelatin, glycerin and aloe vera which are considered as ideal materials for hemostasis activities and encourages cleaning and protection from reinjures or infection and speeds wound healing along with real-time monitoring of pH of wound using carbon dots fluorescence. Conclusion: This work is an attempt to devise a wound dressing that can aid in natural blood-clotting mechanism (sparing blood loss) and providing positive environment in wound healing.
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Aim: Wound is a fragile and complex injury which can be as simple as a minor cut to the deep lesions and traumatic gash. Depending on the patient’s internal and external conditions, wounds can progress backward or forward. Acute hemorrhage and wound infections are the main cause of loss of life in critical conditions of war field or in traumatic accidents. Innovation: BioFibGel bandage/dressing is a green nanotechnology based wound care product which is intended to be used in trauma, combat injuries (bleeding gunshot wounds) and mangling as first-line emergency tool. The dressing can absorb and retain significant amount of water without dissolving or losing their structure, stabilize blood flow and avert bleeding. Materials and Results: BioFibGel is silver nanoparticles based hydrogel sheets/ fibers made up of gelatin, glycerin and aloe vera which are considered as ideal materials for hemostasis activities and encourages cleaning and protection from reinjures or infection and speeds wound healing along with real-time monitoring of pH of wound using carbon dots fluorescence. Conclusion: This work is an attempt to devise a wound dressing that can aid in natural blood-clotting mechanism (sparing blood loss) and providing positive environment in wound healing.

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