New alkaloid from derris indica (lam) bennett seed oil: isolation and characterization
By: Nuzhat Tabassum
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Contributor(s): Vidyasagar, G. M.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2021Edition: Vol.13(4).Description: 56-59p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
International journal of pharmacy and pharmaceutical scienceSummary: Objective: The aim of the study was to isolate alkaloid compound from seed oil of Derris indica(Lam) Bennett where relevant antimicrobial properties in traditional medicines. Methods: The plant was selected based on their usage in traditional medicines and ethnopharmacological importance. Crude extract from D. indicaseeds fractioned with different solvents through column chromatography. Isolated pure fraction was identified and characterized using UV, FTIR, 1HNMR and Mass spectroscopy. Results: D. indica seeds hexane extract on fractionation with ethyl acetate and methanol through column chromatography yielded a crystalline fraction. The fraction was identified as alkaloid group and characterized as a 2-(6-methoxyphenanthridin-8-yl) propan-2-ol. The compound is a new report from D. indicaseed oil.Conclusion: The usage of D. indica plant is much in traditional health care for treatment of diseases. Isolation of alkaloid compound from D. indicaseeds in traditional herbal medicines may be found a good source of drug discovery.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-0471 |
Objective: The aim of the study was to isolate alkaloid compound from seed oil of Derris indica(Lam) Bennett where relevant antimicrobial properties in traditional medicines. Methods: The plant was selected based on their usage in traditional medicines and ethnopharmacological importance. Crude extract from D. indicaseeds fractioned with different solvents through column chromatography. Isolated pure fraction was identified and characterized using UV, FTIR, 1HNMR and Mass spectroscopy. Results: D. indica seeds hexane extract on fractionation with ethyl acetate and methanol through column chromatography yielded a crystalline fraction. The fraction was identified as alkaloid group and characterized as a 2-(6-methoxyphenanthridin-8-yl) propan-2-ol. The compound is a new report from D. indicaseed oil.Conclusion: The usage of D. indica plant is much in traditional health care for treatment of diseases. Isolation of alkaloid compound from D. indicaseeds in traditional herbal medicines may be found a good source of drug discovery.
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