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Hydrodynamically balanced drug delivery system of ranitidine hydrochloride

By: V Ravi Sankar N.
Contributor(s): Reddy, Y. Dastagiri.
Publisher: Haryana International Science Press 2018Edition: Vol.9(1), Jan-June.Description: 65-72-p.Subject(s): PHARMACEUTICS In: Indian journal of pharmaceuticsSummary: Sustain drug absorption from oral controlled release dosage forms is often limited due to short gastric retention time. However, hydrodynamically balanced system (HBS) type dosage forms remain in the stomach for several hours due to their modified GRT. It has been suggested that due to their density and relatively large size they do not pass through the pylorus that has an opening of approximately 0.9 - 1.9 cm.It is worth considering here that a prolonged GRT is not responsible ....
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Sustain drug absorption from oral controlled release dosage forms is often limited due to short gastric retention time. However, hydrodynamically balanced system (HBS) type dosage forms remain in the stomach for several hours due to their modified GRT. It has been suggested that due to their density and relatively large size they do not pass through the pylorus that has an opening of approximately 0.9 - 1.9 cm.It is worth considering here that a prolonged GRT is not responsible ....

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