Effect of types of cyclodextrin on rousvastation calcium inclusion complex
By: Akbari, B. V
.
Contributor(s): Vekariya, H.
Publisher: Haryana International Science Press 2018Edition: Vol.9(1), Jan-June.Description: 79-86p.Subject(s): PHARMACEUTICS
In:
Indian journal of pharmaceuticsSummary: Rosuvastatin calcium is poorly water soluble drug and it exhibit unsatisfactory dissolution profiles and consequently, problems of absorption and poor bioavailability. The aim of this work was to improve solubility and dissolution profile of rosuvastatin by exploiting the solubilizing effect of B-cyclodextrin and hydroxy propyl B-cyclodextrin (HP-2-CD). Rosuvastatin calcium (RST), a poorly water-soluble 3-hydroxy3-methyl glut aryl CoA(HMG-CoA)reductase inhibitor through inclusion complexation with B-cyclodextrin and hydroxy propyl.......
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-1017 |
Total holds: 0
Rosuvastatin calcium is poorly water soluble drug and it exhibit unsatisfactory dissolution profiles and consequently, problems of absorption and poor bioavailability. The aim of this work was to improve solubility and dissolution profile of rosuvastatin by exploiting the solubilizing effect of B-cyclodextrin and hydroxy propyl B-cyclodextrin (HP-2-CD). Rosuvastatin calcium (RST), a poorly water-soluble 3-hydroxy3-methyl glut aryl CoA(HMG-CoA)reductase inhibitor through inclusion complexation with B-cyclodextrin and hydroxy propyl.......
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