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Effect of ploygonum bistorta and tannic acid on hepatic morphological analysis in CCI intoxicated rats

By: Mittal, Deepak Kumar.
Contributor(s): Joshi, Deepmala.
Publisher: Haryana International Science Press 2018Edition: Vol.9(1), Jan-June.Description: 93-95p.Subject(s): PHARMACEUTICS In: Indian journal of pharmaceuticsSummary: Hepatoprotective effect of the aqueous extract of polygounm bistorta linn. (100 mg/kg) and tannic acid (25 mg/kg) in rats treated with carbon tetrachloride (0.15 ml/kg, i.p.). Extract and T A at the tested doses demonstrated profound steatosis degeneration and nodule formation were observed in the hepatic architecture of carbon tetrachloride treated rats which were found to acquire near to normal in extract and TA with carbon tetrachloride administrated rats, and supported the biochemical observations. This study suggests that tannic acid has more liver protective effect in comparison to extract of P. bistorta against carbon tetrachloride-induced hepatotoxicity.
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Hepatoprotective effect of the aqueous extract of polygounm bistorta linn. (100 mg/kg) and tannic acid (25 mg/kg) in rats treated with carbon tetrachloride (0.15 ml/kg, i.p.). Extract and T A at the tested doses demonstrated profound steatosis degeneration and nodule formation were observed in the hepatic architecture of carbon tetrachloride treated rats which were found to acquire near to normal in extract and TA with carbon tetrachloride administrated rats, and supported the biochemical observations. This study suggests that tannic acid has more liver protective effect in comparison to extract of P. bistorta against carbon tetrachloride-induced hepatotoxicity.

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