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Studies on formulation and in vitro evaluation of glimepiride floating tablets

By: Reichal, C. Rubina.
Contributor(s): Bhagya Lakshmi J.
Publisher: Haryana International Science Press 2021Edition: Vol.12(2), Jul-Dec.Description: 63-65p.Subject(s): PHARMACEUTICS In: Indian journal of pharmaceuticsSummary: Floating matrix tablets of glimepiride were developed to porlong the gastric residence time and thereby increased drug bioavailability. Diabetes condition influuences the gastric emptying time which affect the absorption of the drug. Glimepiride was chosen as model drug because it has incomplete obsorption due to less gastric residence time. The tablets were prepared by direct compression technique, using various grades of rate controlling polymers, carbopol 934P either alone or in combination and other standard excipients.....
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Floating matrix tablets of glimepiride were developed to porlong the gastric residence time and thereby increased drug bioavailability. Diabetes condition influuences the gastric emptying time which affect the absorption of the drug. Glimepiride was chosen as model drug because it has incomplete obsorption due to less gastric residence time. The tablets were prepared by direct compression technique, using various grades of rate controlling polymers, carbopol 934P either alone or in combination and other standard excipients.....

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