Evaluation of antioxidant, antimicrobial, cytotoxic potential and elemental analysis of filago desertorum whole plant
By: Abida Bano
.
Contributor(s): Nadia Mushtaq.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2021Edition: Vol.83(6), Nov-Dec.Description: 1243-1253p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical sciencesSummary: The present study aimed to evaluate the ethanolic extract of Filago desertorum for its probable antioxidant,
antimicrobial, cytotoxicity potential and to assess its elemental analysis. The ethanolic extract showed
maximum 2,2-diphenyl-1-picrylhydrazyl (68.48 %), 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid
(71.32 %) and hydrogen peroxide (69.44 %) scavenging activity as compared to ascorbic acid (reference)
at the concentration of 250 μg/ml. The maximum total antioxidant activity (71.53 %) and reducing power
(0.197) were observed at a concentration of 250 μg/ml. The extract showed maximum percent inhibition
against fungal strain Aspergillus fumigates (90 %) and bacterial strain Staphylococcus aureus (10 mm).
The maximum percent mortality (70 %) was determined at 250 μg/ml concentration with half maximal
inhibitory concentration of 127.00 μg/ml. Elemental analysis showed that the sodium (92.936 mg/ml) was
found to be present in large amount while zinc (0.060 mg/g) was found present in low concentration but
cobalt was not detected. Based on the current results, it can be concluded that Filago desertorum has
maximum inhibitory, antimicrobial, cytotoxic potential and therefore can lead to antioxidant, anticancer
and antibiotics agents.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-1248 |
The present study aimed to evaluate the ethanolic extract of Filago desertorum for its probable antioxidant,
antimicrobial, cytotoxicity potential and to assess its elemental analysis. The ethanolic extract showed
maximum 2,2-diphenyl-1-picrylhydrazyl (68.48 %), 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid
(71.32 %) and hydrogen peroxide (69.44 %) scavenging activity as compared to ascorbic acid (reference)
at the concentration of 250 μg/ml. The maximum total antioxidant activity (71.53 %) and reducing power
(0.197) were observed at a concentration of 250 μg/ml. The extract showed maximum percent inhibition
against fungal strain Aspergillus fumigates (90 %) and bacterial strain Staphylococcus aureus (10 mm).
The maximum percent mortality (70 %) was determined at 250 μg/ml concentration with half maximal
inhibitory concentration of 127.00 μg/ml. Elemental analysis showed that the sodium (92.936 mg/ml) was
found to be present in large amount while zinc (0.060 mg/g) was found present in low concentration but
cobalt was not detected. Based on the current results, it can be concluded that Filago desertorum has
maximum inhibitory, antimicrobial, cytotoxic potential and therefore can lead to antioxidant, anticancer
and antibiotics agents.
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