Strategies for the suitability of self-assembled supramolecular polymersomes in drug delivery and diagnostics
By: Bharkatiya, Meenakshi
.
Contributor(s): Sharma, Komal.
Publisher: Karnataka Association of Pharmaceutical Teachers of India (APTI) 2022Edition: Vol.56(3), Jul-Sep.Description: 608-617p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical education and researchSummary: Amphiphilic copolymers which can self-organize into distinct nano vesicles comprising
of hydrophilic core and a hydrophobic bilayer membrane with innumerable morphologies
have wide applications ranging from cell mimics to diagnostics. The flexibility to control
the size, shape, morphology, functionality and surface properties makes polymersomes
widely acceptable. The suitability of these systems for various biomedical applications
exhilarated because of its robust responsiveness to both internal and external stimuli at
the site of interest. The biodegradability with lesser toxicity adds up to its acceptability as
an innate cargo molecule. A large share of research works published on the polymersomes
in recent years showcase this vesicle as a future device of choice for targeted drug
delivery and bio imaging. But the effectiveness of these systems meticulously relays on
the precise engineering of physical, morphological and surface characteristics supported
by thorough understanding on the various aspects of its designing. With an intention
of accelerating multiple dimensions of polymersome research, this article focuses on
recapitulating those controllable essential attributes of polymersomes. It also reveals
how changes in these variables contribute to polymersomes becoming an important
potential freight moiety for a variety of biomedical relevence.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-1360 |
Amphiphilic copolymers which can self-organize into distinct nano vesicles comprising
of hydrophilic core and a hydrophobic bilayer membrane with innumerable morphologies
have wide applications ranging from cell mimics to diagnostics. The flexibility to control
the size, shape, morphology, functionality and surface properties makes polymersomes
widely acceptable. The suitability of these systems for various biomedical applications
exhilarated because of its robust responsiveness to both internal and external stimuli at
the site of interest. The biodegradability with lesser toxicity adds up to its acceptability as
an innate cargo molecule. A large share of research works published on the polymersomes
in recent years showcase this vesicle as a future device of choice for targeted drug
delivery and bio imaging. But the effectiveness of these systems meticulously relays on
the precise engineering of physical, morphological and surface characteristics supported
by thorough understanding on the various aspects of its designing. With an intention
of accelerating multiple dimensions of polymersome research, this article focuses on
recapitulating those controllable essential attributes of polymersomes. It also reveals
how changes in these variables contribute to polymersomes becoming an important
potential freight moiety for a variety of biomedical relevence.
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