Phytochemical analysis, tuberculosis effect, purification and characterization of aerial parts of avicennia alba
By: Michael, R. A. Zerubabel
.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2022Edition: Vol.84(2), Mar-Apr.Description: 423-435p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical sciencesSummary: The present study deals with phytochemical, pharmacological (In vitro antioxidant), purification and
characterization studies of aerial parts of Avicennia alba. The phytochemical analysis for qualitative
and quantitative investigation revealed the presence of more bioactive compounds in methanolic extract
than hexane and chloroform extracts of Avicennia alba. The methanolic extract showed better activity
on 2,2-diphenyl-1-picrylhydrazyl free radical than remaining free radical tests i.e hydrogen peroxide
and hydroxyl radical. The methanolic extract was potent in inhibiting the free radicals upon comparison
with standard ascorbic acid. The tuberculosis effect of the plant was not up to the mark when compared
with standard control. The methanolic plant extract was subjected to column chromatography and three
compounds were isolated. The isolated compounds were characterized by ultraviolet, fourier transform
infrared spectroscopy, proton nuclear magnetic resonance, carbon nuclear magnetic resonance and mass
spectral data studies and were identified as stigmasterol, beta-sitosterol and lupeol. The work carried out
was distinctive as the source of plant was taken from coringa mangrove, Kakinada, first of its kind and the
tuberculosis effect was also reported for the first time, though it was not up to the mark the work reported
inspires the researcher to enlighten and save their time. The natural compounds selected were reported
previously but an in depth characterization was reported for a thorough look.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-2184 |
The present study deals with phytochemical, pharmacological (In vitro antioxidant), purification and
characterization studies of aerial parts of Avicennia alba. The phytochemical analysis for qualitative
and quantitative investigation revealed the presence of more bioactive compounds in methanolic extract
than hexane and chloroform extracts of Avicennia alba. The methanolic extract showed better activity
on 2,2-diphenyl-1-picrylhydrazyl free radical than remaining free radical tests i.e hydrogen peroxide
and hydroxyl radical. The methanolic extract was potent in inhibiting the free radicals upon comparison
with standard ascorbic acid. The tuberculosis effect of the plant was not up to the mark when compared
with standard control. The methanolic plant extract was subjected to column chromatography and three
compounds were isolated. The isolated compounds were characterized by ultraviolet, fourier transform
infrared spectroscopy, proton nuclear magnetic resonance, carbon nuclear magnetic resonance and mass
spectral data studies and were identified as stigmasterol, beta-sitosterol and lupeol. The work carried out
was distinctive as the source of plant was taken from coringa mangrove, Kakinada, first of its kind and the
tuberculosis effect was also reported for the first time, though it was not up to the mark the work reported
inspires the researcher to enlighten and save their time. The natural compounds selected were reported
previously but an in depth characterization was reported for a thorough look.
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