Comprehensive study on provesicular drug delivery system: proniosomal gel
By: Govindarajan, Sangeetha
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Contributor(s): Swamivelmanickam, M.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2022Edition: Vol.84(1), Jan-Feb.Description: 1-13p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical sciencesSummary: Vesicular approaches are novel techniques for transporting the drug that reinforces the availability of drugs
and gives an action for a prolonged time. Besides, it has definite advantages over traditional drug delivery
systems. Liposomes and niosomes comprising vesicles demonstrate the stability issues such as aggregation,
leakage, fusion and sedimentation of vesicles due to the aqueous nature of the system. The provesicular
system developed to overcome these problems for a unique novel approach includes proliposomes and
proniosomes. Provesicles are dry, anhydrous formulations, coated with a non-ionic surfactant, acts as a
carrier mixed with water when needed. This article reviews provesicular drug delivery systems with a focus
on composition, preparation, the mechanism of drug delivery, encapsulation of the drug into provesicles
and characterization techniques. Likewise, this review details the summary of research findings and patent
reports on proniosomal investigations. As supported by the literature study, the proniosomes are a leading
carrier for the delivery of various drugs over different routes of administration.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-2213 |
Vesicular approaches are novel techniques for transporting the drug that reinforces the availability of drugs
and gives an action for a prolonged time. Besides, it has definite advantages over traditional drug delivery
systems. Liposomes and niosomes comprising vesicles demonstrate the stability issues such as aggregation,
leakage, fusion and sedimentation of vesicles due to the aqueous nature of the system. The provesicular
system developed to overcome these problems for a unique novel approach includes proliposomes and
proniosomes. Provesicles are dry, anhydrous formulations, coated with a non-ionic surfactant, acts as a
carrier mixed with water when needed. This article reviews provesicular drug delivery systems with a focus
on composition, preparation, the mechanism of drug delivery, encapsulation of the drug into provesicles
and characterization techniques. Likewise, this review details the summary of research findings and patent
reports on proniosomal investigations. As supported by the literature study, the proniosomes are a leading
carrier for the delivery of various drugs over different routes of administration.
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