Evaluation of anti-ulcer and anti-diarrhoeal activities of the ayurvedic formulation udumbara ghanasatwa
By: Muduli, N
.
Contributor(s): Bose, A.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2022Edition: Vol.84(1), Jan-Feb.Description: 49-57p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical sciencesSummary: Udumbara Ghanasatwa is a classical Ayurvedic formulation prescribed for the treatment of gastritis,
indigestion and diarrhoea without any scientific validation of its pharmacological action. The present
study investigated the antiulcer activity of Udumbara Ghanasatwa at two graded doses by pylorus ligation
model in rats. The anti-diarrhoeal activity was also evaluated in terms of the defecation amount/frequency
as well as intestinal fluid enteropooling in castor oil induced diarrhoea. The Ghanasatwa exerted significant
protective effects in both pylorus ligation-induced gastric ulcer and castor oil induced diarrhoeal models in
a dose-dependent manner. Findings obtained in the study justified the clinical applications of Udumbara
Ghanasatwa in the treatment of gastric ulcers and diarrhoea. These pharmacological effects exerted by
Ghanasatwa may be attributed to the antioxidant phytoconstituents like flavonoids and tannins present
in it.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-2218 |
Udumbara Ghanasatwa is a classical Ayurvedic formulation prescribed for the treatment of gastritis,
indigestion and diarrhoea without any scientific validation of its pharmacological action. The present
study investigated the antiulcer activity of Udumbara Ghanasatwa at two graded doses by pylorus ligation
model in rats. The anti-diarrhoeal activity was also evaluated in terms of the defecation amount/frequency
as well as intestinal fluid enteropooling in castor oil induced diarrhoea. The Ghanasatwa exerted significant
protective effects in both pylorus ligation-induced gastric ulcer and castor oil induced diarrhoeal models in
a dose-dependent manner. Findings obtained in the study justified the clinical applications of Udumbara
Ghanasatwa in the treatment of gastric ulcers and diarrhoea. These pharmacological effects exerted by
Ghanasatwa may be attributed to the antioxidant phytoconstituents like flavonoids and tannins present
in it.
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