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Evaluation of antifungal activity of some plant extractives

By: Nidiry, E. S. J.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2022Edition: Vol.84(1), Jan-Feb.Description: 223-226p.Subject(s): PHARMACEUTICSOnline resources: Click here In: Indian journal of pharmaceutical sciencesSummary: In vitro antifungal activity of thirty two extractives of seven plants obtained using hexane, ethyl acetate and methanol were tested against the mycelial growth of Colletotrichum gloeosporioides. Among these extractives, ethyl acetate extractives of onion seeds, chilli seeds and chilli pericarps and methanol extractives of chilli seeds and chilli pericarps exhibited more than 20 % mycelial growth inhibition at a concentration of 0.5 % level. Methanol extractives of Solanum viarum berries and ethyl acetate extractive of soybean leaves exhibited more than 20 % mycelial growth inhibition at a concentration of 1.0 % level. Thin layer chromatographic bioautography showed that hexane and ethyl acetate extractives of onion seeds, chilli seeds and chilli pericarps exhibited spore germination inhibition of Cladosporium cucumerinum at a dose of 1.0 mg.
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In vitro antifungal activity of thirty two extractives of seven plants obtained using hexane, ethyl acetate
and methanol were tested against the mycelial growth of Colletotrichum gloeosporioides. Among these
extractives, ethyl acetate extractives of onion seeds, chilli seeds and chilli pericarps and methanol extractives
of chilli seeds and chilli pericarps exhibited more than 20 % mycelial growth inhibition at a concentration
of 0.5 % level. Methanol extractives of Solanum viarum berries and ethyl acetate extractive of soybean
leaves exhibited more than 20 % mycelial growth inhibition at a concentration of 1.0 % level. Thin layer
chromatographic bioautography showed that hexane and ethyl acetate extractives of onion seeds, chilli
seeds and chilli pericarps exhibited spore germination inhibition of Cladosporium cucumerinum at a dose
of 1.0 mg.

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