Recent advances and appropriate use of niosomes for the treatment of skin cancer
By: Pottathil, Shinu
.
Contributor(s): Nair, Anroop B.
Publisher: Bangalore Association of Pharmaceutical Teachers of India (APTI) 2022Edition: Vol.56(4), Oct-Dec.Description: 924-937p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical education and researchSummary: Both melanoma and non-melanoma are the most common types of skin cancers affecting
various populations across the globe. Skin malignancy is more prevalent among Caucasian
populations. Non-melanoma types of skin cancers are further classified as basal cell and
squamous cell carcinomas, respectively. The incidence of non-melanoma type of cancers
is relatively higher than melanoma type of skin cancers. Recently published data shows
that melanoma of the skin stands as the seventeenth most common type of cancer across
the world. Niosome is a drug carrier in a novel drug delivery system wherein the drug is
enclosed within the vesicle, which is made up of non-ionic surfactants that are stabilized
by the addition of cholesterol. Niosomes help to overcome certain difficulties of skin
drug deliveries such as insolubility, instability, low bioavailability, and fast debasement
of medications. This review article mainly focuses on the use of niosomes in dermatology
particularly aiming at the delivery of drugs via skin. In addition, this review discusses
the specific use of niosomal drug delivery systems that may be useful in clinics. The
niosomes are gaining popularity in the field of topical drug delivery due to their excellent
characteristics like proficiency to carry both hydrophilic and lipophilic drugs, increasing
the penetration of drugs, and enhancing drug stability and drug release at sustained
levels.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
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School of Engineering & Technology Archieval Section | Not for loan | 2023-0088 |
Both melanoma and non-melanoma are the most common types of skin cancers affecting
various populations across the globe. Skin malignancy is more prevalent among Caucasian
populations. Non-melanoma types of skin cancers are further classified as basal cell and
squamous cell carcinomas, respectively. The incidence of non-melanoma type of cancers
is relatively higher than melanoma type of skin cancers. Recently published data shows
that melanoma of the skin stands as the seventeenth most common type of cancer across
the world. Niosome is a drug carrier in a novel drug delivery system wherein the drug is
enclosed within the vesicle, which is made up of non-ionic surfactants that are stabilized
by the addition of cholesterol. Niosomes help to overcome certain difficulties of skin
drug deliveries such as insolubility, instability, low bioavailability, and fast debasement
of medications. This review article mainly focuses on the use of niosomes in dermatology
particularly aiming at the delivery of drugs via skin. In addition, this review discusses
the specific use of niosomal drug delivery systems that may be useful in clinics. The
niosomes are gaining popularity in the field of topical drug delivery due to their excellent
characteristics like proficiency to carry both hydrophilic and lipophilic drugs, increasing
the penetration of drugs, and enhancing drug stability and drug release at sustained
levels.
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