Face mask embedded with nanoemulsion for reducing facial skin adverse effects caused by prolonged wearing the mask during covid-19 management
By: Alsantali, Reem I
.
Contributor(s): El-Enin, Hadel A. Abo.
Publisher: Bangalore Association of Pharmaceutical Teachers of India (APTI) 2022Edition: Vol.56(4), Oct-Dec.Description: 1083-1090p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical education and researchSummary: Background: Wearing a facemask is one of the precautionary measures for preventing
coronavirus disease spread, which causes many facial skin adverse effects. Vitamin-E
(TPGS) and olive oil have an efficient effect on skin moistening. Therefore, in this study,
face-masks embedded with NE; prepared using olive oil and TPGS, were developed to
reduce the long-wearing face mask adverse effect. Methods: Box-Behnken design was
used to develop NE formulations which were physically evaluated to select the most
stable formulation. Fibroblast cell lines (3T3) were used to examine NE efficacy on dermal
cell proliferation and
in vitro cytotoxicity possibilities. Face-masks were also examined
for 6 hr wearing dermal compatibility on healthy participants. Results: The formulated
NE didn’t significantly affect cell proliferation nor had a toxic effect on dermal cells
(
p<0.05). More than 60% of the respondents were satisfied with masks containing NE.
Conclusion: In particular, a face mask embedded with the preparaed selected NE formula
could produce emollient feelings during application without retarding the breathing or
causing any irritant sensation.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
|
School of Pharmacy Archieval Section | Not for loan | 2023-0105 |
Background: Wearing a facemask is one of the precautionary measures for preventing
coronavirus disease spread, which causes many facial skin adverse effects. Vitamin-E
(TPGS) and olive oil have an efficient effect on skin moistening. Therefore, in this study,
face-masks embedded with NE; prepared using olive oil and TPGS, were developed to
reduce the long-wearing face mask adverse effect. Methods: Box-Behnken design was
used to develop NE formulations which were physically evaluated to select the most
stable formulation. Fibroblast cell lines (3T3) were used to examine NE efficacy on dermal
cell proliferation and
in vitro cytotoxicity possibilities. Face-masks were also examined
for 6 hr wearing dermal compatibility on healthy participants. Results: The formulated
NE didn’t significantly affect cell proliferation nor had a toxic effect on dermal cells
(
p<0.05). More than 60% of the respondents were satisfied with masks containing NE.
Conclusion: In particular, a face mask embedded with the preparaed selected NE formula
could produce emollient feelings during application without retarding the breathing or
causing any irritant sensation.
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