Pharmaceutical standardization of astercantha longifolia kshara
By: Joshi, Khushbu B
.
Contributor(s): Nariya, Mukesh B.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2022Edition: Vol.14(11).Description: 60-64p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
International journal of pharmacy and pharmaceutical scienceSummary: Objective: The present study was aimed for establishment of SMP (standard manufacturing procedure) of Astercantha longifolia (A. longifolia) kshara and to develop its quality control parameter. Methods: The kshara was prepared as per the AFI (Ayurvedic Formulary of India) guideline and for the purpose of standardization three batches were prepared and its mean and standard deviation was calculated.Results: In the present study it was discovered that the average percentage yield of 3 batches of A. longifoliaksharaobtained from a completely dried whole plant 0.81% w/w. Physico-chemical analysis of powder showed foreign matter to be less than 1% w/w, loss on drying 27.5 % w/w, total ash less than 9%, acid insoluble ash to be less than 1%, water soluble extractive value and alcohol soluble extractive value as 10.78% w/w and 5.45 % w/w respectively and pH to be 7.3 which is in accordance with quality standards to be preserved, also Physico-chemical parameters applied to kshara revealsloss on drying as 13.35% w/w and pH to be slightly basic in nature i.e., 7.93. Conclusion: Many references in the classics are mentioned regarding the preparation of kshara; however, as per the findings of the present study, it might be concluded that this method is the standard method to get the maximum yield of A. longifolia kshara.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2023-0262 |
Objective: The present study was aimed for establishment of SMP (standard manufacturing procedure) of Astercantha longifolia (A. longifolia) kshara and to develop its quality control parameter. Methods: The kshara was prepared as per the AFI (Ayurvedic Formulary of India) guideline and for the purpose of standardization three batches were prepared and its mean and standard deviation was calculated.Results: In the present study it was discovered that the average percentage yield of 3 batches of A. longifoliaksharaobtained from a completely dried whole plant 0.81% w/w. Physico-chemical analysis of powder showed foreign matter to be less than 1% w/w, loss on drying 27.5 % w/w, total ash less than 9%, acid insoluble ash to be less than 1%, water soluble extractive value and alcohol soluble extractive value as 10.78% w/w and 5.45 % w/w respectively and pH to be 7.3 which is in accordance with quality standards to be preserved, also Physico-chemical parameters applied to kshara revealsloss on drying as 13.35% w/w and pH to be slightly basic in nature i.e., 7.93. Conclusion: Many references in the classics are mentioned regarding the preparation of kshara; however, as per the findings of the present study, it might be concluded that this method is the standard method to get the maximum yield of A. longifolia kshara.
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