Efficient conjugate addition of 3-methyl-5-pyrazolones to chalcones in water extract rice straw ash (WERSA)
By: Lakshmi, Shanta Raj
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Contributor(s): Singh, Vipin.
Publisher: New Delhi CSIR 2022Edition: Vol.61, Jan.Description: 94-98p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: Conjugate addition of 5-methyl-pyrazolones to chalcone has been described with Water Extract Rice Straw Ash (WERSA) as the reaction medium. Various chalcones have been used as Michael acceptors against 5-methyl-pyrazolones. The products have been isolated in analytically pure form by simple filtration in good to excellent yields under green reaction conditions with good substrate scope. This general eco-friendly method uses waste material for organic transformation. The synthesised compounds could be further utilised for the synthesis of bioactive molecules and pharmaceutical products.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2023-0680 |
Conjugate addition of 5-methyl-pyrazolones to chalcone has been described with Water Extract Rice Straw Ash (WERSA) as the reaction medium. Various chalcones have been used as Michael acceptors against 5-methyl-pyrazolones. The products have been isolated in analytically pure form by simple filtration in good to excellent yields under green reaction conditions with good substrate scope. This general eco-friendly method uses waste material for organic transformation. The synthesised compounds could be further utilised for the synthesis of bioactive molecules and pharmaceutical products.
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