Green synthesis and antibacterial/fungal studies of two new Schiff base derived from 4-(imidazol-1-yl)benzaldehyde
By: Feng, Xiaojun
.
Contributor(s): Wang, Fangkuo.
Publisher: New Delhi CSIR 2022Edition: Vol.61(3), Mar.Description: 298-304p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: This study synthesizes two new Schiff bases, (E)-1-(4-1H-imidazol-1-yl)phenyl)-N-(o-tolyl)methanimine and (E)-1-(4-(1H-imidazol-1-yl)phenyl)-N-(m-tolyl)methanimine through condensation reaction between 4-(imidazol-1-yl)benzaldehyde and 2-toluidine/o-toluidine, respectively. FT-IR, X-ray diffraction and 1H NMR spectroscopy have been carried out to characterize the structure of the products. Through antibacterial/ antifungal activity tests performed using 8 kinds of bacteria/fungus, it is found that the both of the two Schiff bases can suppress the growth of Staphylococcus, Bacillus subtilis and Salmonella, showing good potential as antibacterial drug.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2023-0715 |
This study synthesizes two new Schiff bases, (E)-1-(4-1H-imidazol-1-yl)phenyl)-N-(o-tolyl)methanimine and (E)-1-(4-(1H-imidazol-1-yl)phenyl)-N-(m-tolyl)methanimine through condensation reaction between 4-(imidazol-1-yl)benzaldehyde and 2-toluidine/o-toluidine, respectively. FT-IR, X-ray diffraction and 1H NMR spectroscopy have been carried out to characterize the structure of the products. Through antibacterial/ antifungal activity tests performed using 8 kinds of bacteria/fungus, it is found that the both of the two Schiff bases can suppress the growth of Staphylococcus, Bacillus subtilis and Salmonella, showing good potential as antibacterial drug.
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