One-pot Michael addition and cyclo-elimination cascade synthesis of thiazolo-[ 4,5- b]pyridin- 6-carbonitrile scaffold
By: Tiwari, Shailendra
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Contributor(s): Singh, Vishal Kumar.
Publisher: New Delhi CSIR 2022Edition: Vol.61(10), Oct.Description: 1097-1102p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: A series of thiazolo [4,5-b]- pyridine-6-carbonitriles scaffold have been synthesized conveniently and smoothly in a single step in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria fungi. The minimum inhibitory concentration (MBC) and minimum fungicidal concentration (MFC) have been determined for the test compounds as well as for reference standards. Compounds 3c, 3d, 3e, 3f, 4c, 4d, 4e and 4f have shown good antibacterial as well as antifungal activity.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2023-0816 |
A series of thiazolo [4,5-b]- pyridine-6-carbonitriles scaffold have been synthesized conveniently and smoothly in a single step in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria fungi. The minimum inhibitory concentration (MBC) and minimum fungicidal concentration (MFC) have been determined for the test compounds as well as for reference standards. Compounds 3c, 3d, 3e, 3f, 4c, 4d, 4e and 4f have shown good antibacterial as well as antifungal activity.
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