Bioassay for total serum bioactivity of Atractylodes lancea
By: Na-Bangchang, Kesara
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Contributor(s): Cheoymang, Anurak
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Publisher: Mumbai Wolter Kluwer 2023Edition: Vol.14(1), Jan-Mar.Description: 51-55p.Subject(s): PHARMACEUTICS![](/opac-tmpl/bootstrap/images/filefind.png)
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School of Pharmacy Archieval Section | Not for loan | 2023-1116 |
The study aimed to establish a bioassay for total bioactivity of Atractylodes lancea (AL) in human serum samples. Inhibition of bacterial growth (Staphylococcus aureus ATCC 25923) was assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The calibration curve (0, 0.39, 0.78, 1.56, 3.13, 2.56, and 50 ng/μl) was linear with correlation coefficients >0.990. The limit of quantification (LOQ) was 1.66 mg/ml using 20-ml serum sample. The developed bioassay method meets the standard of the bioanalytical method for determination of serum bioactivity of AL.
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