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Feto-maternal and neonatal complications associated with hypothyroidism in pregnancy

By: Sabbithi, Sunanda.
Contributor(s): Prasanna, Mudham Sai.
Publisher: Bhopal Innovare Academic Sciences Pvt Ltd 2023Edition: Vol.15(12), Dec.Description: 37-42p.Subject(s): PHARMACEUTICSOnline resources: Click here In: International journal of pharmacy and pharmaceutical scienceSummary: Objective: To analyze and report the maternal, fetal, and neonatal complications in Antenatal hypothyroid women and to give the frequency of the co-existence of Anemia with Hypothyroidism in pregnancy. Methods: A Prospective and an observational study was conducted on 200 Antenatal hypothyroid women admitted to the Obstetrics ward. In the period of 6 mo (August 2022-January 2023), the study was carried out through the examination of medical records of Antenatal women with Hypothyroidism. Results: Of 200 Antenatal hypothyroid women enrolled in the study, Denovo Hypothyroidism was seen in 56% of women. Maternal complications reported include–(Lower Segment Cesarean Section) LSCS seen in 54.5%, Preeclampsia in 19%, mild anemia in 28%, (Post-Partum Hemorrhage) PPH in 7.5%,(Premature Rupture Of Membranes) PROM in 11.5%, Oligohydramnios in 24.5% of women. Fetal complications found were in fetal distress in 21%, in 32.5 %, Respiratory distress in 17.5%, and Low birth weight in 16% of Neonates. Conclusion: Our study concludes that the number of pregnant women affected by Hypothyroidism has increased to a larger extent. Hence, the suspected risk factors of Hypothyroidism have to be addressed and monitored closely to decrease the rate of feto-maternal and neonatal complications in pregnancy, vital for the overall well-being of hypothyroid mothers and their babies.
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Objective: To analyze and report the maternal, fetal, and neonatal complications in Antenatal hypothyroid women and to give the frequency of the co-existence of Anemia with Hypothyroidism in pregnancy.

Methods: A Prospective and an observational study was conducted on 200 Antenatal hypothyroid women admitted to the Obstetrics ward. In the period of 6 mo (August 2022-January 2023), the study was carried out through the examination of medical records of Antenatal women with Hypothyroidism.

Results: Of 200 Antenatal hypothyroid women enrolled in the study, Denovo Hypothyroidism was seen in 56% of women. Maternal complications reported include–(Lower Segment Cesarean Section) LSCS seen in 54.5%, Preeclampsia in 19%, mild anemia in 28%, (Post-Partum Hemorrhage) PPH in 7.5%,(Premature Rupture Of Membranes) PROM in 11.5%, Oligohydramnios in 24.5% of women. Fetal complications found were in fetal distress in 21%, in 32.5 %, Respiratory distress in 17.5%, and Low birth weight in 16% of Neonates.

Conclusion: Our study concludes that the number of pregnant women affected by Hypothyroidism has increased to a larger extent. Hence, the suspected risk factors of Hypothyroidism have to be addressed and monitored closely to decrease the rate of feto-maternal and neonatal complications in pregnancy, vital for the overall well-being of hypothyroid mothers and their babies.

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