Ayurveda and transdisciplinary approaches : a way forward towards personalized and preventive medicine
By: Swathi, K
.
Contributor(s): Sundaravadivelu, Sumathi
.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2024Edition: Vol.85(6), Nov-Dec.Description: 1572-1583p.Subject(s): PHARMACEUTICS
Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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School of Pharmacy Archieval Section | Not for loan | 2025-0887 |
Ayurveda is an age-old medicinal practice gaining global acceptance because of its personalized approaches
toward healthcare. The current review focusses on the concepts of Ayurveda and the science behind the
traditional knowledge of Ayurveda by combining transdisciplinary approaches, enabling an evidence-based
framework. The foremost principle of Ayurveda is to understand tridoshas (Vata, Kapha, Pitta) and Prakriti
(inherent nature of individual) to determine the individual’s susceptibility to diseases and treatment regimen. In
the clinical field, reverse pharmacology can unravel the mechanism of documented Ayurvedic medications, thus
facilitating knowledge transfer. Ayurveda positively impacts both phenotypes (Deha Prakriti) and genotypes
(Janma Prakriti) through epigenetics by addressing lifestyle behaviour, diet, stress and environmental factors.
As a result, the modern biology and Ayurveda will better correlate and understand each other through the
Ayurgenomics approach, which outlines the substantial variances in biochemical and genome-wide analysis of
differential prakriti phenotype. The protein targets and lead molecule of an ayurvedic drug can be retrieved
from traditional knowledge-based information databases involving Ayurinformatics. The impact of Ayurveda's
lifestyle and diet principle can be explored through Ayurnutrigenomics, which untangles how Ahara (Diet)
and Pathya (diet-dietetics) foster wellness by influencing the phenotype and genetic makeup of an individual
with respect to tridoshas. Tridoshas has its own house for the gut flora, underlining the significant association
between Prakriti and the microbiome's composition as well as psychobiotics. Incorporating these approaches
in Ayurveda could make a paradigm shift between traditional and modern medicine by providing scientific
validation to Ayurvedic medicines, thereby aiding health management.
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