Digital gangrene induced by inadvertent intra‑arterial cocktail injection of anesthetic agents such as pentazocine, promethazine, and atropine: A serious adverse drug experience
By: Mahajan, Sonia Shinde
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Contributor(s): Tandon, Vishal R | Sarin, Rajat.
Publisher: Mumabi Wolter Kluwer 2018Edition: Vol. 50(6), November-December.Description: 354-357p.Subject(s): PHARMACOLOGY | Anesthetic agents | Atropine | Digital gangrene | Pentazocine | PromethazineOnline resources: Click here
In:
Indian Journal of PharmacologySummary: Gangrenous changes in skin due to accidental intra‑arterial injection of promethazine and pentazocine have been reported. Accidental intra‑arterial injection is most commonly encountered in the antecubital fossa. However, recent reports in the radial and ulnar arteries have also been encountered. We hereby report a serious, preventable adverse drug experience in the form of digital gangrene induced by inadvertent intra‑arterial cocktail injection of anesthetic agents such as pentazocine, promethazine, and atropine, which seems to be in the radial artery as the lateral three digits and dorsum of the hand are affected.
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School of Pharmacy Archieval Section | Not for loan | 2018290 |
Gangrenous changes in skin due to accidental intra‑arterial injection of promethazine and pentazocine have been reported. Accidental intra‑arterial injection is most commonly encountered in the antecubital fossa. However, recent reports in the radial and ulnar arteries have also been encountered. We hereby report a serious, preventable adverse drug experience in the form of digital gangrene induced by inadvertent intra‑arterial cocktail injection of anesthetic agents such as pentazocine, promethazine, and atropine, which seems to be in the radial artery as the lateral three digits and dorsum of the hand are affected.
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