Case study on beta blockers induced psoriasis
By: Rajan, Asha K.
Contributor(s): Jeyamani, Vedha Pal | Kaviya, U.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2019Edition: Vol. 2(3).Description: 112-115p.Subject(s): PHARMACEUTICSOnline resources: Click here In: International journal of pharmacy and pharmaceutical scienceSummary: Drug -induced Psoriasis is one among the common etiological factors of Psoriasis reported worldwide . Familiar drugs known to cause psoriasiform eruptions include Anti -malarials, Beta blockers, NSAIDs, Lithium. etc. Certain a ntihype rtensives like ACE inhibitors, d iuretics are also doc umented to have caused psoriatic episo des. A 5 7 y old S outh -Indian m ale patient with a history of Hypertension, Diabetes Mellitus , Atrial Fibrillation for 4 y; was on antihypertensi ve therapy for Hypertension and Atrial Fibrillation with proponolol for past 2 y and m etoprolol initially . H e was presented to the hospital two weeks after switching on to Metoprolol therapy for chief complaints of erythematous scaly lesions especially ove r both the extremities and paronydrial appearance of nails. Initially , he was on Propran olol therapy which was then shifted to Metoprolol due to an appearance of oral lesions in the mouth . Metoprolol was now discontinued and switched on to Atenolol. After 1 -2 w of therapy with Atenolol, the lesions were found to disappear and no recurrence of psoriatic conditions were found. Proper reviewing of medical history for any allergic reactions and the optimization of drug therapy through Therapeutic Drug Monitoring could be initiated by C linical Pharmacist in order to avoid such drug -induced flares.Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database | School of Pharmacy Archieval Section | Not for loan | 2018569 |
Drug
-induced
Psoriasis is one among the common etiological factors of Psoriasis
reported worldwide
. Familiar drugs known to cause psoriasiform
eruptions include Anti
-malarials, Beta blockers, NSAIDs, Lithium.
etc.
Certain a
ntihype
rtensives like ACE inhibitors, d
iuretics are also doc
umented
to have caused psoriatic
episo
des.
A 5
7 y
old S
outh
-Indian m
ale patient with a
history of Hypertension, Diabetes
Mellitus
, Atrial Fibrillation for
4 y;
was on antihypertensi
ve
therapy
for Hypertension and Atrial Fibrillation with
proponolol
for past 2 y
and m
etoprolol
initially
. H
e was presented to the hospital two weeks
after
switching on to
Metoprolol therapy for chief complaints of erythematous scaly lesions especially
ove
r both
the extremities and
paronydrial
appearance of nails.
Initially
, he
was
on Propran
olol therapy which was then shifted to Metoprolol
due to an
appearance
of oral lesions in
the
mouth
.
Metoprolol was now
discontinued and
switched on to Atenolol. After 1
-2 w
of therapy with Atenolol, the lesions were found to disappear and no
recurrence of
psoriatic conditions were found.
Proper reviewing of medical history
for any allergic reactions
and
the
optimization
of drug therapy through Therapeutic Drug
Monitoring could be
initiated by C
linical Pharmacist in order to avoid such drug
-induced flares.
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