ANTIVIRAL DRUGS FOR INFLUENZA VIRUSES
- Vol.11(5)
- M P Innovare Academic Sciences Pvt Ltd 2019
- 1-8p.
Antiviral drugs have significant action against inf luenza viruses A and B. Virus spread deadly disease in which many people die, and the country economy greatly suffer. Presently, most of the peop le need to get vaccination, which is depending on t he dose limit in humans. It reacts directly or sometimes indirectly in the form of metabolites. How ever, it is mandatory to know how much drug is abso rbed or metabolites concentration after administered. Therefore, pharmacokinetics data is v ery crucial for all drugs. Our review discusses the mechanism of drugs action and their activity and also describes how antiviral drugs and their me tabolites are determined using highly sensitive ins truments such as high-performance liquid chromatography (HPLC), ultra-pressure liquid chromat ography (UPLC), and mass spectrometry (MS). Therefo re, the present review gives brief information about antiviral drugs, their activity, biotransformation and analytical methods for quanti fication and this information will be helpful for any future studies done by experts in this field an d will be beneficial for research scientists and in fluenza experts of all over the globe.