Ruwali, Pushpa <br/><br/>
PHYTOCHEMICAL AND ANTIOXIDANT PROPERTIES OF VARIOUS  EXTRACTS OF  MICHELIA  CHAMPACA  LEAVES 

 - Vol.11(5) 
 - M P  Innovare Academic Sciences Pvt Ltd  2019 
 - 56-61p. 
<br/><br/> Objective<br/>:<br/>To  investigate  and  compare  the  phytochemical<br/>s,  antioxidant  activities  of  <br/>various<br/>  crude  extracts  from  fresh  leaves  of  locally  available  <br/>plant<br/>Michelia<br/> champaca<br/> belonging to family Magnoliaceae.  <br/>Method<br/>s: <br/>The <br/>present study was designed to perform preliminary phytochemical (qualitative and quantit<br/>ative<br/>) analysis of various extracts. The crude <br/>extracts from the leaves <br/>of <br/>M. champaca<br/>were prepared using various<br/> organic<br/> solvents<br/>viz<br/>.<br/> Methanol (MCMET), Ethanol (MCETH), Hexane (MCHEX), and <br/>Chloroform  (MCCHLO).  In  addition,  total  phenolic  (TPC)  and  total<br/>  flavonoid  (TFC)  contents  of  various  extracts  were  also  measured  along  with  the  <br/>evaluation of the antioxidant capacities using most widel<br/>y accepted <br/>in vitro<br/> chemical tests such as DPPH and ABTS radical scavenging assay.<br/>Result<br/>s: <br/>The <br/>methanolic  extract<br/> of <br/>M. champaca<br/>showed the presence of maximum phytochemicals (12) when compared to other solvent extracts <br/>viz. <br/>Hexane   (10),   Ethanol   (8)   and   <br/>Chloroform(7).   The   amount   of   phenolic   and   flavonoids   present   in   solvents   were   in   the   order   of   <br/>Methanol<br/>>Hexane<br/>>Ethanol<br/>>Chloroform. The best antioxidant potential was found in the<br/> Methanol extract. The <br/>Methanolic extract exhibited an IC<br/>50<br/>Conclusio<br/>n: <br/>Phytochemical  analysis  of  <br/>M.  champaca<br/>(leave<br/>s)  various <br/>extracts  showed  good<br/>  amount<br/>s  of  phenolic  and  flavonoid  contents<br/>  and  also  <br/>exhibited  significant  antioxidant  activity<br/>.  A  positive  linear  correlation  between  the <br/>antioxidant  activities  and  the  total  phenolic  and  flavonoid  <br/>contents <br/>of the plant extracts was observed. <br/>Study revealed variations in suc<br/>h reported activities due to different organic extracti<br/>on solvents used. <br/>In  overall  conclusion,  <br/>Michelia<br/>  champaca<br/>  has  good  potential  as  a  source  of  natural  antioxidant  for  animal<br/>  health  and  food  industry  and  further  <br/>relevant studies on similar lines would be worthwhile. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACEUTICS