Singh, Ajay Pal

New antimicrobial pentacyclic triterpenoid from the rhizomes of Nardostachys jatamansi DC. - Vol.58(B), April - New Delhi CSIR 2019 - 516-521p.

Phytochemical investigation of Nardostachys jatamansi rhizomes has resulted in isolation of a new pentacyclic triterpenoid lup-20 (29)-en-3β-olyl-3β--galactofuranosyl-6'-octadec-9''-enoate 4 along with three phytoconstituents characterized as 1-octadec-9',10'-dienoyl-2,3-n-dioctadecanoyl glycerol 1, n-octanyl-n-octadecanoate 2, n-nonyloctadecanoate 3. The structures of all the isolated compounds have been elucidated on the basis of spectral data analysis such as IR, 1H and 13C NMR, mass spectroscopy and chemical reactions. Compounds 1, 2, 3 have been reported first time from Nardostachys genus. The isolated phytoconstituents have been tested for antimicrobial activity against bacterial and fungal strains. Only compound 4 shows antimicrobial activity.


GENERAL CHEMISTRY