Sharaf, Eman F.  <br/><br/>
In vitro antifungal activity of some indigenous medicinal plant extracts against five isolates of aspergillus fumigatus 

 - Vol.83(4), July-Aug 
 - Mumbai  Indian Journal of Pharmaceutical Science  2021 
 - 695-700p. 
<br/><br/> There is a constant exposure of humans to Aspergillus mold fungus and 95 % of the pathogenic species.<br/>It is important to study drugs with new efficacy against infections because of increased prevalence of<br/>infections resistant to antibiotics. The present study aims to assess the antifungal activity of aqueous and<br/>ethanol plant extracts (cinnamon, garlic, ginger and guava) against five isolates of the opportunistic mold<br/>Aspergillus fumigatus. The results showed that effect of ethanol and aqueous extracts of cinnamon was<br/>same on all the five isolates of Aspergillus fumigatus. The recorded diameters of inhibition zone for isolates<br/>1, 2, 3, 4 and 5 exerted by the cinnamon ethanol extracts were 41, 46, 40, 45 and 46 mm respectively.<br/>Moreover, ginger was excluded in next experiments because all the isolates showed resistance against<br/>the aqueous and ethanol extract of ginger, except for isolate 5. Minimum inhibitory concentration was<br/>2 mg/ml ethanol extract of garlic and cinnamon whereas that of aqueous extract of garlic and cinnamon was<br/>40 mg/ml and 10 mg/ml, respectively. The study concluded that ethanol extract of cinnamon can be used<br/>as antimycotic agent against Aspergillus fumigatus to treat diseases but it is urged to detect the sensitivity<br/>of fungal isolate to the extract before using as different responses are provided by isolates in a wide range<br/>of extracts. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACEUTICS