Thamaraiselvi, L. <br/><br/>
In silico molecular docking on bioactive compounds from indian medicinal plants against type 2 diabetic target proteins: a computational approach 

 - Vol.83(6), Nov-Dec 
 - Mumbai  Indian Journal of Pharmaceutical Science  2021 
 - 1273-1279p. 
<br/><br/> Natural chemical compounds from medicinal plants used for the healing of diseases and disorders with<br/>fewer side effects, easy accessibility and economically cheap. The current study was aimed at finding novel<br/>drug like molecules as anti-diabetic compounds using in silico approach. Intermolecular interactions<br/>between target proteins and different antidiabetic compounds were observed. Five phytocompounds were<br/>selected from Plumbago zeylanica, Neolitsea cassia and Wrightia tinctoria and taken for molecular docking<br/>against human pancreatic alpha-amylase and human dipeptidyl peptidase IV using Autodock 4.2. Among<br/>the five phyto compounds, 6 urs-12-en-24-oic acid Plumbago zeylanica is the best compound for both the<br/>human pancreatic alpha-amylase and human dipeptidyl peptidase IV inhibition, as it possessed higher<br/>value in molecular dockings. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACEUTICS