Namdev, Bhavesh  <br/><br/>
Brief review on solubility enhancement technique: hydrotropy 

 - Vol.56(2), Apr-Jun 
 - Karnataka  Association of Pharmaceutical Teachers of India (APTI)  2022 
 - 347-355p. 
<br/><br/> In this review we have elaborated about number of hypothesis postulated to understand<br/>the mechanism of hydrotropic agents, although majority of the postulated hypothesis<br/>haven’t justified the solubility enhancement mechanism. Further to it the articles focuses<br/>upon the parameters affecting enhancement of solubilizing ability. Hydrotropes are<br/>extensively used in drug solubilization, extraction agents for various phytoconstituents,<br/>separation agent used for pharmaceutical analysis, as well as for increasing the rate and<br/>yield of a chemical reaction due to their unique features. Because of this, hydrotropic<br/>solutions possess high industrial demand. While mixed hydrotropy is mostly used in<br/>enhancement of solubility, extraction of phytoconstituents and separation by the use<br/>of more than one hydrotropic agent. This review article also highlights the applications<br/>and future prospects with the employment of hydrotropes and hydrotropic agents in<br/>novel drug delivery or parental or oral or tropical systems to enhance solubility profile the<br/>drugsare also discussed. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACEUTICS