Giramkar, Shital Ashok  <br/><br/>
Comparative evaluation of triphala extract prepared using two methods 

 - Vol.84(2), Mar-Apr 
 - Mumbai  Indian Journal of Pharmaceutical Science  2022 
 - 513-518p. 
<br/><br/> In view of the wide usage of Triphala for large number of therapeutic indications, ethno medicinal practice<br/>of extract preparation viz. extracting the three plants together (sample A) and mixing the extracts of<br/>three plants prepared separately (sample B), were compared. Both the test samples were analyzed with<br/>respect to their physicochemical, phytochemical and pharmacological profiles. In case of physicochemical<br/>properties, ash values and moisture content of both samples were comparable. Sample A showed less acidic<br/>nature and high water soluble extractive (96.15±1.7) value which was statistically significant (p<0.05).<br/>Phytochemical estimation of gallic acid and ellagic acid by high-performance thin-layer chromatography<br/>showed higher content in sample B (-97.7 ng/μg) and sample A (-49.2 ng/μg) respectively. Pharmacological<br/>activity of both the samples was comparable for total phenol content, total antioxidant and free radical<br/>scavenging activity. Although both samples inhibited the activities of acetylcholine esterase and lipase in<br/>a concentration dependent manner; sample B showed better activity. Usually, multi-plant extracts were<br/>proven more superior over single plant extracts. In our study extract prepared by mixing the extracts of<br/>3 plants prepared separately showed better pharmacological activity profile than the extract prepared by<br/>extracting the three plants togethers. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACEUTICS