Rajan, Asha K. <br/><br/>
Case study on beta blockers induced psoriasis 

 - Vol. 2(3) 
 - M P  Innovare Academic Sciences Pvt Ltd  2019 
 - 112-115p. 
<br/><br/> Drug<br/>-induced <br/>Psoriasis is one among the common etiological factors of Psoriasis<br/> reported worldwide<br/>. Familiar drugs known to cause psoriasiform <br/>eruptions include Anti<br/>-malarials, Beta blockers, NSAIDs, Lithium. <br/>etc.<br/> Certain  a<br/>ntihype<br/>rtensives  like  ACE  inhibitors,  d<br/>iuretics are also doc<br/>umented <br/>to have caused psoriatic<br/> episo<br/>des. <br/>A 5<br/>7  y<br/> old  S<br/>outh<br/>-Indian m<br/>ale  patient  with a <br/>history of Hypertension, Diabetes<br/> Mellitus<br/>,  Atrial  Fibrillation  for  <br/>4    y; <br/>was on antihypertensi<br/>ve <br/>therapy <br/>for  Hypertension  and  Atrial  Fibrillation  with  <br/>proponolol<br/>  for  past  2  y<br/>  and  m<br/>etoprolol<br/>  initially<br/>.  H<br/>e  was  presented  to  the  hospital  two  weeks  <br/>after <br/>switching  on  to  <br/>Metoprolol  therapy  for  chief  complaints  of  erythematous  scaly  lesions  especially  <br/>ove<br/>r  both <br/>the  extremities  and  <br/>paronydrial<br/>appearance of nails. <br/>Initially<br/>, he <br/>was <br/>on Propran<br/>olol therapy which was then shifted to Metoprolol<br/> due to an <br/>appearance<br/> of oral lesions in <br/>the <br/>mouth<br/>. <br/>Metoprolol  was  now <br/>discontinued  and  <br/>switched on to Atenolol. After 1<br/>-2  w<br/>  of  therapy  with  Atenolol,  the  lesions  were  found  to  disappear  and  no  <br/>recurrence of <br/>psoriatic conditions were found.<br/>Proper reviewing of medical history<br/> for any allergic reactions<br/> and <br/>the <br/>optimization<br/> of drug therapy through Therapeutic Drug<br/> Monitoring could be <br/>initiated by C<br/>linical Pharmacist in order to avoid such drug<br/>-induced flares. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACEUTICS