Darekar, M.

Synthesis and antimicrobial evaluation of 3,4-dihydropyrimidin-2(1H)-on analogs - Vol.56(5), May - Mumbai Indian Drug Manufacture's Association - IDMA 2019 - 59-63p.

This paper reports synthesis of functionalized 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) via a three component condensation reaction. The synthesized molecules were tested against bacterial strains Bacillus subtilis and Escherechia coli and against fungal strains Candida albicans and Aspergillus niger.Compounds 4d, 4h, 4l, 4p were found to exhibit very moderate antibacterial activity while compounds 4d, 4l showed very moderate antifungal activity as compared to standards ciprofloxacin and fluconazole


PHARMACEUTICS