Ansari, Nishat <br/><br/>
ANTIOXIDANT STUDIES ON METHANOL AND AQUEOUS EXTRACTS OF  GYMNOSPORIA  MONTANA  PLANT 

 - Vol.11(2) 
 - M P  Innovare Academic Sciences Pvt Ltd  2019 
 - 65-70p. 
<br/><br/> Objective: <br/>The  main  objective  of  this  study  was  to  evaluate  the  free  radical  scavenging  activity  of  methanol<br/>  (70%)<br/>  and  aqueous  extract  of  <br/>G. <br/>montana <br/>leaves <br/>which is a <br/>traditionally used herb known for <br/>its hepatoprotective activity<br/>. <br/>Method<br/>s: <br/>The <br/>in vitro<br/> antioxidant <br/>activity<br/> of   <br/>G. montana <br/>extract <br/>was determined using <br/>1, 1<br/>-diphenyl<br/>-2-picrylhydrazyl radical (DPPH)<br/>,<br/> 2,2<br/>′<br/>-azin<br/>obis<br/>-<br/>(3<br/>-ethylbenzothiaziline<br/>-6-sulfonate  (ABTS),  Hydrogen  p<br/>eroxide  scavenging  activity<br/>,  Superoxide  anion  radical  scavenging  activity  and  Reducing  <br/>Power ability at <br/>three <br/>different concentrations<br/> (1.78μg<br/>/ml<br/>, 3.57μg/ml<br/> and 7.14μg/ml<br/>).  <br/>Result<br/>s: <br/>The<br/>Result<br/>s  revealed  similar  observations<br/>  between  the  methanol  and  aqueous  extract  with  respect  to  standard  and  showed  potent  <br/>antioxidant activity. Ascorbic acid was used as <br/>a standard<br/>, which showed IC<br/>50 <br/>Conclusio<br/>n: <br/>Findings <br/>indicate<br/> that this<br/> plant is a good source of antioxidant and can be used for <br/>the <br/>treatment <br/>of diseases as<br/> such<br/> medicinal plant <br/>extracts are natural products and they are comparatively safe, eco<br/>-friendly, less expensive and locally available. Hence, the validation of the effects <br/>of these herbal remedies will have to be undertaken for<br/> their wider acceptance.   
<br/><br/><label>Subjects--Topical Terms: </label><br/>PHARMACEUTICS