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005 | 20200923144650.0 | ||
008 | 200923b xxu||||| |||| 00| 0 eng d | ||
040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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100 |
_912593 _aMuhammad Torequl Islam |
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245 | _aIn vitro Anti-atherothrombosis Activity of Nigella sativa Oil, Phytol and their Combinations | ||
250 | _aVol.53(4), Oct-Dec | ||
260 |
_aKarnataka _bAssociation of Pharmaceutical Teachers of India (APTI) _c2019 |
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300 | _a670-674p. | ||
520 | _aBackground: Black seed oil and Phytol (PHY) are evident for their promising biological effects in various test systems. Aim: This study evaluates anti-atherothrombosis activity of Nigella sativa oil (NSO) and Phytol (PHY). Materials and Methods: The clotlysis activity of the NSO and/or PHY has been investigated by taking Streptokinase (SK) as a standard clotlysis drug. Results: The results suggest that the NSO and PHY exhibited a concentration-dependent clotlysis activity in human clotted blood. The highest clotlysis of the NSO and PHY was seen by 57.83 ± 0.23% and 53.05 ± 2.93% with 80 μL and 150 μg per tube, respectively. NSO co-treated with PHY showed a better clotlysis capacity than the NSO and PHY. The vehicle showed negligible clotlysis (2.86 ± 4.33%) capacity, while the standard SK (100 I.U.) showed 78.96 ± 1.08% clotlysis activity. Conclusion: NSO and/or PHY exhibited clotlysis activity in human clotted blood in in vitro. | ||
650 | 0 |
_94639 _aPHARMACEUTICS |
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700 |
_912594 _aMolla, Shamim |
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773 | 0 |
_x0019-5464 _dBengluru Association of Pharmaceutical Teachers of India (APTI) _tIndian journal of pharmaceutical education and research |
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856 |
_uhttps://www.ijper.org/sites/default/files/IndJPhaEdRes_53_4_670_1.pdf _yClick here |
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942 |
_2ddc _cAR |