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999 _c11484
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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _912593
_aMuhammad Torequl Islam
245 _aIn vitro Anti-atherothrombosis Activity of Nigella sativa Oil, Phytol and their Combinations
250 _aVol.53(4), Oct-Dec
260 _aKarnataka
_bAssociation of Pharmaceutical Teachers of India (APTI)
_c2019
300 _a670-674p.
520 _aBackground: Black seed oil and Phytol (PHY) are evident for their promising biological effects in various test systems. Aim: This study evaluates anti-atherothrombosis activity of Nigella sativa oil (NSO) and Phytol (PHY). Materials and Methods: The clotlysis activity of the NSO and/or PHY has been investigated by taking Streptokinase (SK) as a standard clotlysis drug. Results: The results suggest that the NSO and PHY exhibited a concentration-dependent clotlysis activity in human clotted blood. The highest clotlysis of the NSO and PHY was seen by 57.83 ± 0.23% and 53.05 ± 2.93% with 80 μL and 150 μg per tube, respectively. NSO co-treated with PHY showed a better clotlysis capacity than the NSO and PHY. The vehicle showed negligible clotlysis (2.86 ± 4.33%) capacity, while the standard SK (100 I.U.) showed 78.96 ± 1.08% clotlysis activity. Conclusion: NSO and/or PHY exhibited clotlysis activity in human clotted blood in in vitro.
650 0 _94639
_aPHARMACEUTICS
700 _912594
_aMolla, Shamim
773 0 _x0019-5464
_dBengluru Association of Pharmaceutical Teachers of India (APTI)
_tIndian journal of pharmaceutical education and research
856 _uhttps://www.ijper.org/sites/default/files/IndJPhaEdRes_53_4_670_1.pdf
_yClick here
942 _2ddc
_cAR